화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Macromolecular Research, Vol.22, No.11, 1141-1151, November, 2014
DOI10.1007/s13233-014-2184-9  Export Citation
Molecular imaging for In vivo tracking of stem cell fate
Kyoung Soo Lee1, Eun Ji Kim1, Ji Suk Choi1, Ick Chan Kwon2, and Yong Woo Cho1, 2, †
  • 1Department of Chemical Engineering, Hanyang University, Ansan, Gyeonggi, 426-791, Korea
  • 2Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Seoul, 136-791, Korea
E-mail:
Stem cells have a potential to dramatically change the common modalities of treatment for many diseases. Despite their rapid transition from animal studies to clinical applications, a number of unanswered questions remain regarding in vivo behaviors of stem cells transplanted into target tissues, including questions about their survival, distribution, migration, differentiation, and tumorigenicity. Recent advances in noninvasive molecular imaging technologies, including optical imaging, magnetic resonance imaging (MRI), radionuclide imaging, and reporter genebased imaging, have gradually elucidated the fundamental behaviors of stem cells via in vivo real time qualitative and quantitative monitoring. Here, we briefly review current imaging techniques for tracking stem cells, with an emphasis on the advantages and drawbacks of each imaging approach, and discuss future prospects for in vivo tracking of stem cells in regenerative medicine.
Keywords:stem cell;molecular imaging;in vivo tracking;regenerative medicine
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