Pyrolysis of Milkweed was carried out in a thermogravimetric analyzer and a bubbling fluidized bed reactor. Total liquid yield of Milkweed pyrolysis was between 40.74% and 44.19 wt% between 425 degrees C and 550 degrees C. The gas yield increased from 27.90 wt% to 33.33 wt% with increasing reaction temperature. The higher heating values (HHV) of the Milkweed bio-oil were relatively high (30.33-32.87 MJ/kg) and varied with reaction temperature, feeding rate and fluidization velocity. The selectivity for CO2 was highest within non-condensable gases, and the molar ratio of CO2/CO was about 3 at the different reaction conditions. The C-13 NMR analysis, of the bio-oil showed that the relative concentration carboxylic group and its derivatives was higher at 425 degrees C than 475 degrees C, which resulted in slightly higher oxygen content in bio-oil. The pH of aqueous phase obtained at 475 degrees C was 7.37 which is the highest reported for any lignocellulosic biomass pyrolysis oils. (C) 2014 Elsevier Ltd. All rights reserved.