The low-temperature dehydrogenation of propane with O-2 and H-2 on H3PMo12O40-modified Pt catalysts has been studied and improvement of the catalyst performance achieved with the aid of promoters and operating conditions. Introduction of phosphoric acid into the catalysts results in a more uniform distribution of heteropoly acid and enables the content of Pt to be decreased to 0.05 wt.% without affecting catalyst productivity at the low temperature (200 degrees C). With Ag as the promoter, the propane combustion to CO2 can be further lowered and selectivity to propene enhanced to 94%. The best results were obtained when the consumption of H-2 and O-2 along the catalyst bed was compensated with a new portion of the reagents (two reactors in line); propene selectivity was still near 90% at overall propane conversion of 7.5% and propene space-time yield of 370 g kg(cat)(-1) h(-1). The catalysts showed little deactivation and maintained their conversion and selectivity values for the time of the measurements (5-10 h). (C) 2014 Elsevier B.V. All rights reserved.