Cuprous oxide (Cu2O) films and Cu/Cu2O/Cu/FTO sandwich structures were prepared by electrochemical deposition on conductive FTO substrates with different pH value conditions but constant deposition potential. The phase composition, crystal structure and microstructure of the Cu2O films were characterized by XRD, SEM and EDS as well as by Electric-Pulse-Induced-Resistance (EPIR) perturbation. In particular, the switching effects of the Cu/Cu2O/Cu/FTO device are examined in this work. The result shows that the EPIR-effect is large for the Cu/Cu2O/Cu/FTO device at room temperature and strongly related to the pH value of the solution. In both acidic and neutral conditions, for example at pH = 5, 6 and 7, the EPIR effect is significant and decreases with increasing pH value. It disappears when the pH value goes further into the alkaline regime, i.e. pH = 8, 9 and 10. Space charge barriers at the interface of electrode and Cu2O are used to explain the I-V characteristic of the layer structure and the EPIR-effect. (C) 2014 Elsevier B.V. All rights reserved.