Thermal piles or thermo-active foundations utilize heat exchangers embedded within foundation footings to heat and/or cool buildings. In this paper, the impact of thermal piles on building foundation heat transfer is investigated. In particular, a simplified analysis method is developed to estimate the annual ground-coupled foundation heat transfer when buildings are equipped with thermal piles. First, a numerical analysis of the thermal performance of thermo-active building foundations is developed and used to assess the interactions between thermal piles and slab-on-grade building foundations. The impact of various design parameters and operating conditions is evaluated including foundation pile depth, building slab width, foundation insulation configuration, and soil thermal properties. Based on the results of a series of parametric analyses, a simplified analysis method is presented to assess the impact of the thermal piles on the annual heat fluxes toward or from the building foundations. A comparative evaluation of the predictions of the simplified analysis method and those obtained from the detailed numerical analysis. indicated good agreement with prediction accuracy lower than 5%. Moreover, it is found that thermal piles can affect annual building foundation heat loss/gain by up to 30% depending on foundation size and insulation level. (C) 2014 Elsevier Ltd. All rights reserved.