Areas with deep seated radioactive granites are considered targets for enhanced geothermal system (EGS) projects. These areas normally exhibit high heat flow and temperature anomalies related to granitic bodies. High concentrations of uranium within the granites are the most likely cause of the anomalous temperatures. Elevated temperatures are also resulted to high heat flow and thick sedimentary rock cover that includes insulating materials such as coals and gas reservoirs. In this study we investigated the use of 3D seismic amplitudes and attributes to map deep granitic bodies and faults in the Cooper Basin of South Central Australia. We established a workflow for possible geomechanical fluid flow susceptibility analyses for faults that intersect granites. The far field stress tensor must be interpreted through analyses of image logs and formation tests. Our geomechanical analyses models show how this stress tensor affects basement faults interpreted from 3D seismic surveys. Normal stresses, shear stresses, slip tendency, and distance to failure should be modelled for the faults that cut the granites. The optimal orientation of faults that can be possible conduits are then located. We suggest that the optimal injection and production wells should be located at tips of shallow faults that penetrate the granites. We anticipate that short horizontal faults that are located far from other faults will form a more secure fluid conduit. Finally, this study can be a workflow to evaluate the relative merit of future enhanced geothermal system projects. (C) 2014 Elsevier Ltd. All rights reserved.