The purpose of this research is to establish a processing method for a wide-area nanometer scale periodic structure on the surface of a plastic plate in order to improve its hydrophobicity. We also evaluated the effect of a nanoperiodic structure applied in the uniaxial direction. Plastic plates of acrylonitrile-ethylene-styrene with dimensions of 100x100mm(2) with a nanoperiodic structure on their surfaces were fabricated using a femtosecond laser and an injection molding technique. In the injection molding, the maximum transfer ratio for the depth reached as high as 0.79. When the nanoperiodic structure was applied in the uniaxial direction, the apparent contact angles did not decrease with respect to the direction of the ridges. As a result, the apparent contact angle increased by 20.4 degrees, from 77.2 degrees to 97.6 degrees which is equivalent to 26%. In the six-month duration test, the sliding angle was initially decreased by applying the nanoperiodic structure. Additionally, the sliding angle was maintained between 20 degrees and 38.3 degrees during the duration test, which was lower than the angle for the flat plate at 42.7 degrees. It can be considered that the depth was sufficient to maintain the sliding angle. In this condition, the contact angle hysteresis did not differ with or without the nanoperiodic structure on the surfaces, an effect that could be caused by surface dirt. In summary, the plastic plate was well drained and the characteristics were maintained for several months by forming the nanoperiodic structure on the surface.