Olfactory ensheathing cells seeded muscle-stuffed vein as nerve conduit for peripheral nerve repair: A nerve conduction study

Lokanathan Y; Ng MH; Hasan S; Ali A; Mahmod M; Htwe O; Roohi SA; Idrus RBH; Abdullah S; Naicker AS

Journal of Bioscience and Bioengineering, Vol.118, No.2, 231-234, 2014

DOI10.1016/j.jbiosc.2014.02.002 Export Citation

Olfactory ensheathing cells seeded muscle-stuffed vein as nerve conduit for peripheral nerve repair: A nerve conduction study

Lokanathan Y, Ng MH, Hasan S, Ali A, Mahmod M, Htwe O, Roohi SA, Idrus RBH, Abdullah S, Naicker AS

We evaluated bridging of 15 mm nerve gap in rat sciatic nerve injury model with muscle-stuffed vein seeded with olfactory ensheathing cells as a substitute for nerve autograft. Neurophysiological recovery, as assessed by electro-physiological analysis was faster in the constructed biological nerve conduit compared to that of autograft. (C) 2014, The Society for Biotechnology, Japan. All rights reserved.

Keywords:Olfactory ensheathing cells;Muscle-stuffed vein;Nerve conduction study;Compound motor action potential;Latency