We discuss a mechanism for controlled motion of drops with applications for microfluidics and microgravity. The mechanism is the following: a solid plate supporting a liquid droplet is simultaneously subject to lateral and vertical harmonic oscillations. In this way the symmetry of the back-and-forth droplet movement along the substrate under inertial effects is broken and thus will induce a net driven motion of the drop. We study the dependency of the traveled distance on the oscillation parameters (forcing amplitude, frequency, and phase shift between the two perpendicular oscillations) via phase field simulations. The internal flow structure inside the droplet is also investigated. We make predictions on resonance frequencies for drops on a substrate with a varying wettability.