Journal of Fermentation and Bioengineering, Vol.82, No.5, 507-508, 1996
Asymmetric Bioreduction of Benzyl Acetoacetate to Its Corresponding Alcohol, Benzyl (S)-(+)-3-Hydroxybutyrate by the Yeast Candida-Schatavii My-1831
The screening of 35 microbial strains yielded 13 of them as suitable biocatalysts for the asymmetric bioreduction of benzyl acetoacetate to its corresponding alcohol benzyl (S)-(+)-3-hydroxybutyrate. The production of benzyl (S)-(+)-3-hydroxybutyrate with an elevated optical purity of 93% was achieved when employing the yeast Candida schatavii strain MY 1831.