In the present study the selective recovery of cobalt(II) ions from nickel(II) sulphate solution by oxime of 1-(2-pyridyl)tridecan-1-one has been investigated. The studies focused on evaluating the influence of several experimental parameters, such as pH of aqueous solutions, temperature of the process, aqueous/organic phase ratio, and separation factors for cobalt and nickel extraction on the selective recovery of cobalt ions. Based on the results, the flow-sheet for the selective recovery of cobalt ions from nickel sulphate solution was proposed.