Catalysts for biofuels reforming based on two types of nanocomposite active components( Ni + Ru/La0.8Pr0.2Mn0.2Cr0.8O3/Y0.08Zr0.92O2-delta, Ni + Ru/Sm0.15Pr0.15Ce0.35Zr0.35O2) supported on microchannel substrates (Ni-Al alloy foam plates, Fechraloy plates protected by a thin corundumlayer) were developed. Applied procedures for the active components loading on substrates provide thermochemical stability of supported layers of active components in tough operation conditions not affecting their reactivity/catalytic activity. Effects of the nature of nanocomposite active component, type of fuel (ethanol, ethyl acetate, acetone and glycerol), feed composition and contact time on the yield of syngas/byproducts and performance stability are considered and compared with results of calculations of the equilibrium composition of reaction mixtures. For nanocomposite active components with a high oxygen mobility and reactivity, reforming of such typical fuel as ethanol is described by the stepwise red-ox mechanism. Preliminary results of the mathematical modelling of the ethanol steam reforming on a stack of microchannel Fechraloy plates loaded with Ni + Ru/Sm 0.15Pr0.15Ce0.35Zr0.35O2 active component revealed that this process can be satisfactorily described by the isothermal model without any impact of the heat/mass transfer. (C) 2014 Elsevier B.V. All rights reserved.