The catalytic activity of VOx species supported on TiO2 was investigated in the simultaneous destruction of NO and 1,2-dichlorobenzene (o-DCB), as typical pollutants molecules in the off-gases from municipal waste incinerator (MWI) plants. Catalysts with different vanadium loading were prepared in order to obtain different VO, species and characterized by ICP-AES, XPS, N-2 adsorption at -196 degrees C, XRD, H-2-TPR, Raman and UV-vis-NIR DRS spectroscopy. The characterization results show that molecularly dispersed isolated and polymeric vanadia species form below the dispersion limit loading ("monolayer coverage"), while crystalline species form above it. We used moderate HNO3 treatment to partially leach vanadium oxide species, creating a series of catalysts with variable vanadia loading. The catalytic activity of the VOx/TiO2 catalyst shows that it is able to catalyze the destruction of both pollutants, although higher temperature is required for o-DCB oxidation than for NO reduction. Surface vanadia coverage has a clear effect on TOF and activation energy values, which underline that isolated vanadia species are more efficient for o-DCB oxidation, while the polymeric ones are more efficient for NO reduction. (C) 2015 Elsevier B.V. All rights reserved.