Over the past decades, innovations in the design of heat exchangers have improved thermal process efficiency. hiTRAN wire matrix technology is applied on the tube side of tubular heat exchangers and has been successfully used in a wide range of application, ranging from sensible heating and cooling to condensing and boiling services. The technology is used for both new designs and in revamp situations where it can increase the effectiveness of existing equipment. This review gives the required information to determine the process conditions for the most efficient use of this technology.