Cytoprotective effects against UVA and physical properties of luteolin-loaded cationic solid lipid nanoparticle

Yoo Min Jeong; Ji Hoon Ha; Soo Nam Park

Journal of Industrial and Engineering Chemistry, Vol.35, 54-62, March, 2016

DOI10.1016/j.jiec.2015.12.014 Export Citation

Cytoprotective effects against UVA and physical properties of luteolin-loaded cationic solid lipid nanoparticle

Yoo Min Jeong, Ji Hoon Ha, and Soo Nam Park^†

Department of Fine Chemistry, Cosmetic R&D Center, College of Energy and Biotechnology, Seoul National University of Science and Technology, 232, Gongneung-ro, Nowon-gu, Seoul 137-743, Republic of Korea

E-mail:

Solid lipid nanoparticles consisting of cationic lipids were prepared for effective delivery of luteolin, and evaluated their physical characteristics and cytoprotective effects against ultraviolet A (UVA) radiation and H2O2 in HaCaT cells. This study reports that triple-tailed CSLN can enhance transdermal delivery of luteolin with high entrapment efficiency, slow release kinetic without initial burst. Further, it showed high intracellular uptake, provided the highest degree of the cytoprotective effects of LT-CSLNs (83.10%, 77.65%) as compared to non-treated groups (60.85%, 52.70%) against UVA and H2O2. These results suggested that LT-CSLN3 could be used as an effective transdermal delivery system for luteolin.

Keywords:Solid lipid nanoparticle;Luteolin;Drug delivery;Cellular uptake;Cationic lipids

[References]

Jo NR, Park CI, Park CW, Shin DH, Hwang YC, Kim YH, Park SN, Appl. Chem. Eng., 23(2), 183 (2012)
Kim OK, Ho JN, Nam DE, Jun WJ, Lee JM, J. Korean Soc. Food. Sci. Nutr., 42, 608 (2013)
Filipe P, Silva JN, Haigle J, Freitas JP, Fernandes A, Santus R, Morliere P, Photochem. Photobiol. Sci., 4, 420 (2005)
Hseu YC, Chou CW, Kumar KJS, Fu KT, Wang HM, Hsu LS, Kuo YH, Wu CR, Chen SC, Yang HL, Food Chem. Toxicol., 50, 1245 (2012)
Park SN, J. Soc. Cosmet. Sci. Korea, 23, 75 (1997)
Packer L, Ultraviolet Radiation (UVA, UVB) and Skin Antioxidants, Elsevier Science B.V., New York, 1994.
Michael JH, Frederick ED, Free Radic. Biol. Med., 43, 1023 (2007)
Kanofsky JR, Hoogland H, Wever R, Weiss SJ, J. Biol. Chem., 263, 9692 (1988)
Gu HA, Kim MJ, Kim HS, Ha JH, Yu ER, Park SN, Appl. Chem. Eng., 26(2), 165 (2015)
Park E, Kum S, Wang C, Park SY, Kim BS, Schuller-Levis G, Am. J. Chin. Med., 33, 415 (2005)
Xagorari A, Papapetropoulos A, Mavromatis A, Economou M, Fotsis T, Roussos C, J. Pharmacol. Exp. Ther., 296, 181 (2001)
Kotanidou A, Xagorari A, Bagli E, Kitsanta P, Fotsis T, Papapetropoulos A, Roussos C, Am. J. Respir. Crit. Care Med., 165, 818 (2002)
Lee SM, Choi MJ, Lee YM, Jin BS, Appl. Chem. Eng., 21(1), 40 (2010)
Han SB, Kwon SS, Jeong YM, Yu ER, Park SN, Int. J. Cosmet. Sci., 36, 588 (2014)
Kwon SS, Kong BJ, Park SN, Eur. J. Pharm. Biopharm., 92, 146 (2015)
Jeon SH, Yoo CY, Park SN, Colloids Surf. B: Biointerfaces, 129, 7 (2015)
Kim SJ, Kwon SS, Jeon SH, Yu ER, Park SN, Int. J. Cosmet. Sci., 36, 553 (2014)
Muller RH, Mader K, Gohla S, Eur. J. Pharm. Biopharm., 50, 161 (2000)
Wissing SA, Muller RH, Int. J. Pharm., 254, 65 (2003)
Anthony AA, Christel CMG, Colloids Surf. A: Physicochem. Eng. Asp., 315, 189 (2008)
Muhlen A, Schwarz C, Mehnert W, Eur. J. Pharm. Biopharm., 45, 149 (1998)
Tran TH, Choi JY, Ramasamy T, Truong DH, Nguyen CN, Choi HG, Yong CS, Kim JO, Carbohydr. Polym., 114, 407 (2014)
Cavalli R, Peira E, Caputo O, Gasco MR, Int. J. Pharm., 182, 59 (1999)
Casadei MA, Cerreto F, Cesa S, Giannuzzo M, Feeney M, Marianecci C, Paolicelli P, Int. J. Pharm., 325, 140 (2006)
Faabregas A, Saanchez-Hernaandez N, Ticoo JR, Garcıia-Montoya E, Peerez-Lozano P, Sunnee-Negre JM, Hernaandez-Munain C, Sunnee C, Minnarro M, Int. J. Pharm., 473, 270 (2014)
Kuo YC, Lin SC, J. Phys. Chem. B, 112(14), 4454 (2008)
Kuo YC, Wang CC, J. Phys. Chem. C, 116, 16999 (2012)
Kuo YC, Chen HH, Int. J. Pharm., 365, 206 (2009)
Kuo YC, Wang CC, Colloids Surf. B: Biointerfaces, 101, 101 (2013)
Xie S, Zhu L, Dong Z, Wang Y, Wang X, Zhou WZ, Int. J. Nanomed., 6, 547 (2011)
Khurana S, Bedi PMS, Jain NK, Int. J. Biomed. Nanosci. Nanotechnol., 2, 232 (2012)
Tabatt K, Sameti M, Olbrich C, Muller RH, Lehr CM, Eur. J. Pharm. Biopharm., 57, 155 (2004)
Pinnaduwage P, Schmitt L, Huang L, Biochim. Biophys. Acta, 985, 33 (1989)
Proverbio ZE, Schulz PC, Puig JE, Colloid Polym. Sci., 280, 1045 (2002)
Kim BM, (M.S. Dissertation), Department of Chemical Engineering Graduate School of Soongsil University, vol. 161, Republic of Korea, 2011.
Han F, Li S, Yin R, Liu H, Xu L, Colloids Surf. A: Physicochem. Eng. Asp., 315, 210 (2008)
Liu J, Hu W, Chen H, Ni Q, Xu H, Yang X, Int. J. Pharm., 328, 191 (2007)
Lee GS, (M.S. Dissertation), Graduate School of Konkuk University, vol. 89, Republic of Korea, 2008.
Svenson S, Curr. Opin. Colloid Interface Sci., 9, 201 (2004)
Muhlen AZ, Schwarz C, Mehnert W, Eur. J. Pharm. Biopharm., 45, 149 (1998)
Herringson TP, Patlolla RR, Altin JG, J. Gene Med., 11, 1048 (2009)
Provencher SW, Comput. Phys. Commun., 27, 213 (1982)

[Referenced By]

[1] Jo NR, Park CI, Park CW, Shin DH, Hwang YC, Kim YH, Park SN, Appl. Chem. Eng., 23(2), 183 (2012)

[2] Kim OK, Ho JN, Nam DE, Jun WJ, Lee JM, J. Korean Soc. Food. Sci. Nutr., 42, 608 (2013)

[3] Filipe P, Silva JN, Haigle J, Freitas JP, Fernandes A, Santus R, Morliere P, Photochem. Photobiol. Sci., 4, 420 (2005)

[4] Hseu YC, Chou CW, Kumar KJS, Fu KT, Wang HM, Hsu LS, Kuo YH, Wu CR, Chen SC, Yang HL, Food Chem. Toxicol., 50, 1245 (2012)

[5] Park SN, J. Soc. Cosmet. Sci. Korea, 23, 75 (1997)

[6] Packer L, Ultraviolet Radiation (UVA, UVB) and Skin Antioxidants, Elsevier Science B.V., New York, 1994.

[7] Michael JH, Frederick ED, Free Radic. Biol. Med., 43, 1023 (2007)

[8] Kanofsky JR, Hoogland H, Wever R, Weiss SJ, J. Biol. Chem., 263, 9692 (1988)

[9] Gu HA, Kim MJ, Kim HS, Ha JH, Yu ER, Park SN, Appl. Chem. Eng., 26(2), 165 (2015)

[10] Park E, Kum S, Wang C, Park SY, Kim BS, Schuller-Levis G, Am. J. Chin. Med., 33, 415 (2005)

[11] Xagorari A, Papapetropoulos A, Mavromatis A, Economou M, Fotsis T, Roussos C, J. Pharmacol. Exp. Ther., 296, 181 (2001)

[12] Kotanidou A, Xagorari A, Bagli E, Kitsanta P, Fotsis T, Papapetropoulos A, Roussos C, Am. J. Respir. Crit. Care Med., 165, 818 (2002)

[13] Lee SM, Choi MJ, Lee YM, Jin BS, Appl. Chem. Eng., 21(1), 40 (2010)

[14] Han SB, Kwon SS, Jeong YM, Yu ER, Park SN, Int. J. Cosmet. Sci., 36, 588 (2014)

[15] Kwon SS, Kong BJ, Park SN, Eur. J. Pharm. Biopharm., 92, 146 (2015)

[16] Jeon SH, Yoo CY, Park SN, Colloids Surf. B: Biointerfaces, 129, 7 (2015)

[17] Kim SJ, Kwon SS, Jeon SH, Yu ER, Park SN, Int. J. Cosmet. Sci., 36, 553 (2014)

[18] Muller RH, Mader K, Gohla S, Eur. J. Pharm. Biopharm., 50, 161 (2000)

[19] Wissing SA, Muller RH, Int. J. Pharm., 254, 65 (2003)

[20] Anthony AA, Christel CMG, Colloids Surf. A: Physicochem. Eng. Asp., 315, 189 (2008)

[21] Muhlen A, Schwarz C, Mehnert W, Eur. J. Pharm. Biopharm., 45, 149 (1998)

[22] Tran TH, Choi JY, Ramasamy T, Truong DH, Nguyen CN, Choi HG, Yong CS, Kim JO, Carbohydr. Polym., 114, 407 (2014)

[23] Cavalli R, Peira E, Caputo O, Gasco MR, Int. J. Pharm., 182, 59 (1999)

[24] Casadei MA, Cerreto F, Cesa S, Giannuzzo M, Feeney M, Marianecci C, Paolicelli P, Int. J. Pharm., 325, 140 (2006)

[25] Faabregas A, Saanchez-Hernaandez N, Ticoo JR, Garcıia-Montoya E, Peerez-Lozano P, Sunnee-Negre JM, Hernaandez-Munain C, Sunnee C, Minnarro M, Int. J. Pharm., 473, 270 (2014)

[26] Kuo YC, Lin SC, J. Phys. Chem. B, 112(14), 4454 (2008)

[27] Kuo YC, Wang CC, J. Phys. Chem. C, 116, 16999 (2012)

[28] Kuo YC, Chen HH, Int. J. Pharm., 365, 206 (2009)

[29] Kuo YC, Wang CC, Colloids Surf. B: Biointerfaces, 101, 101 (2013)

[30] Xie S, Zhu L, Dong Z, Wang Y, Wang X, Zhou WZ, Int. J. Nanomed., 6, 547 (2011)

[31] Khurana S, Bedi PMS, Jain NK, Int. J. Biomed. Nanosci. Nanotechnol., 2, 232 (2012)

[32] Tabatt K, Sameti M, Olbrich C, Muller RH, Lehr CM, Eur. J. Pharm. Biopharm., 57, 155 (2004)

[33] Pinnaduwage P, Schmitt L, Huang L, Biochim. Biophys. Acta, 985, 33 (1989)

[34] Proverbio ZE, Schulz PC, Puig JE, Colloid Polym. Sci., 280, 1045 (2002)

[35] Kim BM, (M.S. Dissertation), Department of Chemical Engineering Graduate School of Soongsil University, vol. 161, Republic of Korea, 2011.

[36] Han F, Li S, Yin R, Liu H, Xu L, Colloids Surf. A: Physicochem. Eng. Asp., 315, 210 (2008)

[37] Liu J, Hu W, Chen H, Ni Q, Xu H, Yang X, Int. J. Pharm., 328, 191 (2007)

[38] Lee GS, (M.S. Dissertation), Graduate School of Konkuk University, vol. 89, Republic of Korea, 2008.

[39] Svenson S, Curr. Opin. Colloid Interface Sci., 9, 201 (2004)

[40] Muhlen AZ, Schwarz C, Mehnert W, Eur. J. Pharm. Biopharm., 45, 149 (1998)

[41] Herringson TP, Patlolla RR, Altin JG, J. Gene Med., 11, 1048 (2009)

[42] Provencher SW, Comput. Phys. Commun., 27, 213 (1982)