The present work is an experimental investigation of commercial diesel fuel liquid desulfurization via adsorption under mild conditions. The sorbent employed was a commercial high surface area activated carbon (AC), and studies involved both laboratory- and pilot-scale experiments performed in dedicated fixed-bed setups. Under laboratory-scale conditions, maximum sulfur removal measured exceeded 90%, while according to breakthrough curves the total sulfur content remained below 2 ppmw for up to 20-22 mL of processed diesel per gram of sorbent. Process scaling-up by a factor of IS showed a moderate negative effect, with the respective breakthrough fuel amount (total sulfur <= 2 ppmw) being similar to 15-17 mL processed fuel/g sorbent. Several sorbent regeneration strategies were studied under laboratory-scale conditions. The one with the highest restoration of initial (i.e., fresh state) AC performance involved heating under vacuum (200 mbara) up to 200 degrees C and subsequent washing of the material with a binary organic solvent. The amount of solvent required was 50-55 mL/g sorbent. However, even under such conditions, desulfurization performance was only partially restored upon repeated desulfurization/regeneration cycles. From the second and up to the seventh cycle, desulfurization efficiency of the material was essentially stable, but from the eighth cycle and on, further performance degradation was identified. Based on fresh/regenerated sorbent post-analysis, it was found that cycle-to-cycle degradation was due to a gradual decrease of the sorbent's surface area, mainly attributed to residual amounts of diesel-derived species remaining in its structure, thereby partially blocking its porosity. The main properties of processed fuel remained essentially unaffected; however, removal of di- and polyaromatic compounds was notable.