In this study, the effects of diisopropyl ether (DIPE)-gasoline (D10, D20, and D30) fuel blends on the performance, combustion, and emission characteristics of a spark ignition engine were investigated. In the study a four-stroke, four-cylinder multi-point fuel injection system (MPFI) engine with an eddy current dynamometer was used. The tests were performed at speeds between 1400 rpm and 2800 rpm under the load conditions of 20 N m and 25 N m. The results obtained from the DIPE-gasoline blends were compared with gasoline fuel. The DIPE-gasoline blends produced higher brake thermal efficiency, in-cylinder pressure, and heat release rates as compared to gasoline fuel. From emission point of view hydrocarbon (HC) and carbon monoxide (CO) emissions were found lesser, whereas carbon dioxide (CO2) and nitrogen oxide (NOx) emissions were observed higher in case if DIPE-gasoline blends compared to gasoline. However, retarding the ignition timing resulted in reduced NOx emission in DIPE-gasoline blends. (C) 2016 Elsevier Ltd. All rights reserved.