A proton conducting poly(vinylidene fluoride) (PVDF) supported zirconium phosphate (ZrP) ion-exchange membrane (ZrP/PVDF) was synthesized for potential application in DMFC by filling the pores of a PVDF film with in-situ grown ZrP particles. Presence of labile protons attached to P=O group was confirmed from H-1 NMR and FT-IR characterizations. SEM micrographs showed defect-free top surface. The thermal stability and mechanical strength of the ZrP/PVDF membrane was better than Nafion-117. Water to methanol uptake ratio was higher while methanol cross-over for ZRP/PVDF membrane was lower than Nafion-117. Membrane possessed fair electrochemical properties; 0.85 static counter-ion transport number, 0.76 meqg(-1) ion exchange capacity and 1.25 mScm(-1) proton conductivity at 30 degrees C. DMFC performance of the synthesized membrane at 35 degrees C was compared with the Nafion-117. DMFC studies were also done at different operating conditions and the maximum peak power density was 32.3 mWcm(-2) at 60 degrees C, 1 M methanol concentration and 60% relative humidity. Copyright (C) 2015, Hydrogen Energy Publications, LLC. Published by Elsevier Ltd. All rights reserved.