Conventional time-temperature indicators (TTIs) are usually based on various processes, such as the diffusion of colorful solution, color-changing polymerization, enzymatic reactions, and photochromic reactions. In this study, a new type of device based on an electrochemical pseudo-transistor in structured conductive polymers is presented as a with the activation energy closed to results in other studies and products in market. This TTI provides basic functions, such as clock, temperature sensor, and electrical switch. Furthermore, this pseudo-transistor-TTI is combined with radio frequency identification (RFID) technique for the first time. A TTI-RFID label can offer double protection for perishable food by using TTI and RFID readers. This label not only demonstrates that structured conductive polymers can be used as a powerful TTI with an electrical switch but also supplies a new alternative strategy to combine TTI with an RFID tag to supervise and trace the safety of perishable food. (C) 2015 Elsevier Ltd. All rights reserved.