The temperature dependence of a previously developed glucose fuel cell is explored. This cell uses a small molecule dye mediator to transport oxidizable electrons from glucose to a carbon felt anode. This reaction is driven by an air breathing MnO2 cathode. This research investigates how the temperature of the system affects the power production of the fuel cell. Cell performance is observed using either methyl viologen, indigo carmine, trypan blue, or hydroquinone as a mediator at temperatures of 15,19, 27, 32, 37, 42, and 49 degrees C. Cyclic voltammetry of the cell anode at the given temperatures with the individual dyes is also presented. The highest power production amongst all of the cells occurs at 32 degrees C. This occurs with the mediator indigo carmine or with the mediator methyl viologen. These sustained powers are 2.31 mW cm(-2) and 239 mW cm(-2), respectively. This is approximately a 350% increase for these cells compared to their power produced at room temperature. This dramatic increase is likely due to increased solubility of the mediator dye at higher temperatures. (C) 2015 Elsevier B.V. All rights reserved.