The development of advanced catalyst supports is a promising route to obtain active and durable electrocatalysts for methanol electro-oxidation reaction. In the current work, nitrogen-doped carbon encapsulated titanium dioxide composite (TiO2@NCx) is constructed and serves as support material for the Pt catalyst. The TiO2@NCx support is fabricated by the procedure of an in-situ polymerization and subsequent pyrolysis. The synthesized Pt/TiO2@NCx catalysts show enhanced electrocatalytic performance towards methanol electro-oxidation compared with the commercial Pt/C catalyst. The enhancement can be ascribed to combinatory effect of N-doped carbon and TiO2, in which the tolerance to CO-poisoning and the intrinsic kinetics of methanol oxidation reaction are simultaneously improved by the bifunctional mechanism and the electronic effect. As a result, the as-developed TiO2@NCx composite is a promising catalyst support material for the application in fuel cell. (C) 2015 Elsevier B.V. All rights reserved.