Journal of the American Chemical Society, Vol.137, No.10, 3446-3449, 2015
Catalytic Asymmetric Dearomatizing Redox Cross Coupling of Ketones with Aryl Hydrazines Giving 1,4-Diketones
An asymmetric Bronsted acid catalyzed dearromating redbox cross coupling reaction has been realized, in which aryl hydrazines react with ketones to deliver 1,4-diketones, bearing an all-carbon, quarternary stereocenter in high enantiopurity.