Colloidosomes with hollow Anterior and a porous plasmonic shell are highly desired for many applications including nanoteactors, surface enhanced Raman scattering (SERS), photothermal therapy, and controlled drug release. We herein report a silica nanosphere-templated electrostatic self-assembly in conjunction with a newly developed Ag+ soldering to fabricate gold colloidosomes toward multifunctionality and stimuli-responsibility: The gold colloidosomes are capable of Capturing a nano-Sized object and releasing it via structural dissociation upon responding to a biochemical input (GSH, glutathione) at a concentration close to its cellular level: In addition,, the colloidosomes have a tunable nanoporous shell composed of strongly coupled,gold nanoparticles, which exhibit broadened near infrared plasmon resonance. These features along with the Simplicity and high tunability of the fabrication process make the gold colloidosomes quite promising for applications in a chemical or cellular environment.