An efficient, simple, and green procedure for the synthesis of quinoxaline derivatives catalyzed by Fe3O4@SiO2-imid-PMA(n) nanoparticles at room temperature is described. This environmentally benign method provides several advantages such as mild reaction conditions, good to excellent yields, short reaction times, simple work-up and catalyst stability, easy preparation, heterogeneous nature and easy separation of the catalyst. Also, nanocatalyst can be easily recovered by a magnetic field and reused for the next reactions for at least 6 times without distinct deterioration in catalytic activity. SEM, BET, DLS and leaching of catalyst after each reaction cycle were investigated. Furthermore, antiftmgal activity of various derivatives against three phytopathogenic fungi (Altemaria alternata, Pyricularia oryzae, and Alternaria brassicae) was investigated. (C) 2015 Elsevier Ltd. All rights reserved.