Molecular Crystals and Liquid Crystals, Vol.403, 57-65, 2003
Crystal structure and conformation of a pair of piperidine derivatives
N-Morpholinoacetyl-3-methyl-2,6-diphenylpiperidin-4-one(MCAMPO), C24H28 N2O3, F.W = 392.48, monoclinic, P2(1)/c, a = 9.5714(10) Angstrom, b = 19.7588(10)Angstrom, c = 11.3961(10)Angstrom, beta = 94.383(10), V = 2148.9(3)Angstrom(3), Z = 4, D-calc = 1.213 Mg/m(3), mu = 0.639 mm(-1), F-000 = 840, CuKalpha = 1.5418Angstrom, final R1 and wR2 are 0.0509 and 0.1352, respectively. N-Morpholinoacetyl-3-isopropyl-2,6-diphenylpiperidin-4-one(MCAIPO), C26H32N2O3, F.W = 420.54, orthorhombic, P2(1)2(1)2(1), a = 9.0053(2)Angstrom, b = 12.1942(10)Angstrom c = 21.1742(2)Angstrom, V = 2325.19(6)Angstrom(3), Z = 4, D-calc = 1.201 Mg/m(3), mu = 0.078 mm(-1), F-000 = 904, MoKalpha = 0.71073Angstrom final R1 and wR2 are 0.0595 and 0.1151, respectively. The heterocyclic rings of the two ketopiperidines exhibit twist-boat and chair conformations, respectively. The morpholine ring poses an acceptor nitrogen atom for C-H ... N interactions in both. the structures.