As amply reported, after Bhopal disaster process safety got a boost worldwide and risk analysis got applied more generally. Even if the concept of inherent safety, strongly promoted by Trevor Kletz, represents one of the main lessons from this tragedy, in the first part of the paper we focus on Bhopal mitigation measures representing the ultimate relevant layer of protection. Starting from a technical analysis of the whole safety equipment of the plant and relevant empirical evidences, we face the short-cut design of critical safety devices suitable to mitigate release effects. The applied method allows a preliminary design and management tool to evaluate the effectiveness of safety systems and the impact on surroundings. In the second part, we develop an empirical-based framework allowing to identify emergency actions and intervention time and demonstrate how the implementation of these safety measures when reaching a critical pressure of 10 psig in Tank 610, even under the condition of protective equipment out of commission, would have surely mitigated such a high profile tragedy. The paper illustrates the determining contribution to this tragedy of such deficiencies in the safety procedures for handling abnormal situations and emergencies by the company. (C) 2015 The Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.