In this study, the sorption ability of MgAl-NO3 layered double hydroxide prepared by coprecipitation method to remove Cr(VI) from aqueous solution was investigated in fixed-bed column. The sorbent was characterized by XRD, SEM, FTIR, BET surface area, and pH(zpc). The effects of bed height (2-5 cm), flow rate (5-20 mL/min), inlet Cr(VI) concentration (30-100 mg/L), and solution pH (3-8) on the breakthrough characteristics of the column were determined, and the optimum conditions were observed at 3.5 cm, 10 mL/min, 50 mg/L, and a pH of 6. Moreover, the performance of the sorbent to remove Cr(VI) from wastewater was also examined at optimum conditions. The results show high removal and good selectivity for Cr(VI) in wastewater containing large amounts of coexisting anions.