The interfacial tension of poly lactic acid (PLA) melt is measured in supercritical carbon dioxide (CO2) at the temperature range of 143 degrees C to 168 degrees C and CO2 pressures up to 13,790 kpa, using axisymmetric drop shape analysis profile (ADSA-P). The results show a decrease in interfacial tension with increasing temperature and pressure. However, the interfacial tension dependency on temperature at high pressures decreases because of a reduction in CO2 solubility at high temperatures. The relationship between the interfacial tension and the density-difference of polymer-supercritical CO2 mixtures is also examined by the generalized Macleod's equation. Moreover, the range of stability for the melted drop, in interfacial tension measurements, is obtained by dimensionless Bond number. The results indicate the validity of the measurements for Bond number between 0.36 and 0.48. (C) 2015 Elsevier B.V. All rights reserved.