With the use of artificial lipid membranes, it is shown that C-60 fullerenes are capable to penetrate into a lipid bilayer, by locally strengthening its conductivity. C-60 fullerenes tinder the UV/VIS and X-ray irradiation do not influence the MTT reduction and the DNA structure in thymocytes. UV/VIS irradiated C-60, fullerenes give rise to the DNA fragmentation and a decrease of the viability of ascitic Erlich carcinoma cells.