A biomimetic bovine serum albumin proteinhy/droxyapatite coating was prepared by electrochemically co-precipitation on TiAlZr surface. Coating prepared in the presence and in absence of BSA were characterized by Scanning electron microscopy (SEM), Fourier Transformat Infrared microscopy (FTIR), and contact angle measurements. The calcium ion release content was determined using the inductively coupled plasma spectrophotometer (ICP-MS). The advantages of this chip and convenient electrochemical procedure of bioactivation is discussed over the commonly used procedures which prepared phosphate coatings modulate their properties without imitation of the mode in which hydroxyapatite bone crystals are formed in the body.