Turkish Journal of Chemistry, Vol.26, No.3, 379-383, 2002
Efficient synthesis of 1-alkoxycarbonyl-methyl-2-alkylpyrroles from dichloro- and methoxychloropropylalkyl ketones
The condensation reaction of 2,3-dichloropropyl- and 2-methoxy-3-chloropropyl alkyl ketones with alkyl 2-aminoacetate salts leads to 1-alkoxy-carbonylmethyl-2-alkylpyrroles. These compounds, with various bases, gave 1-carbamoylmethyl-, 1-dialkylaminocarbonylmethyl-, 1-carbazoyl methyl-2-alkylpyrroles and potassium salt of 2-alkyl-pyrrolyl-1-acetic acid.