화학공학소재연구정보센터
Turkish Journal of Chemistry, Vol.32, No.5, 585-592, 2008
Synthesis and Antifungal Activity of Some Novel N-(4-Phenyl-3-aroylthiazol-2(3H)-ylidene) Substituted Benzamides
Variously substituted N-(4-phenyl-3-aroylthiazol-2(3H)-ylidene) benzamides (2a-t) were prepared by base-catalyzed cyclization of corresponding 1-aroyl-3-aryl thioureas with acetophenone in the presence of bromine. Some of the synthesized compounds were assayed in vitro for their antifungal activity and were found to exhibit low to moderate activity.