An innovative radiofrequency oxidation technology was developed to treat organic slurries with high solids content. The extent of nutrient release and solids disintegration from separated solids fraction of dairy manure was examined in a pilot scale 6 kW radiofrequency system. The factors affecting the process were hydrogen peroxide dosage, heating time and power intensity of radiofrequency. The newly developed RF oxidation process was highly efficient in releasing orthophosphate and soluble chemical oxygen demand in the treated solution and found to be viable to treat dairy manure. (C) 2015 Elsevier Ltd. All rights reserved.