N-Methyl bis[(nonafluorobutane)sulfonyl]imide (Nf(2)NMe) was synthesized to serve as an initiator for polymerization of 2-oxazolines and the polymerization activity and control of molecular weight were compared with conventional methyl triflate (TfOMe). Ring-opening polymerization of the vinyl-containing 2-oxazoline, 2-(3-butenyl)-2-oxazoline, and a subsequent thiol-ene click reaction and oxidation resulted in the successful synthesis of electrophoretic poly(2-oxazoline)s containing pendent sulfone. It was possible to coat the polymeric sulfones obtained via oxone oxidation (conversion, >99%) on a stainless-steel anode selectively. Furthermore, hybridization of the poly(2-oxazoline)s with bioactive glass (Bioglass45S5) by electrophoretic deposition (EPD) was investigated, and the biocompatibility of the hybrid was also evaluated.