Chemistry Letters, Vol.45, No.1, 24-26, 2016
Structural Basis for Heme Recognition by HmuT Responsible for Heme Transport to the Heme Transporter in Corynebacterium glutamicum
The crystal structure of HmuT from Corynebacterium glutamicum, which is a heme-binding protein in an ABC-type heme transporter system, HmuTUV, has been determined in the bob-form. Heme was accommodated with two different orientations in the central cleft, in which His 141 and Tyr240 were coordinated to the heme as axial ligands.