Membrane filtration processes such as ultrafiltration are increasingly employed in industrial and municipal wastewater treatment. However, these filtration processes are usually poor for removing low molecular weight organic and inorganic contaminants. Micellar enhanced ultrafiltration (MEUF), where contaminants first partition into micellar phases prior to removal by ultrafiltration, has been shown to be an effective removal technique for a variety of trace contaminants in wastewater. To characterize or predict the removal efficiency of MEUF, it is important to have a quantitative measure of the extent to which a species is able to bind to a micelle as well as to develop an understanding of the dynamics of the binding interactions. Herein, we report micellar binding constants for a series of sulfonamide antibiotics (sulfadoxine, sulfathiazole, sulfamethoxazole, sulfamerazine, sulfadiazine, sulfamethazine, sulfacetamide, sulfaguanidine, and sulfanilamide) with cetyltrimethylammonium bromide (CTABr) micelles, as determined using a semi -equilibrium dialysis method. Sulfadoxine, sulfathiazole and sulfamethoxazole exhibited the strongest tendency to bind to CTABr micelles, indicating that they possessed greater potential for removal via MEUF than did sulfanilamide or sulfaguanidine, which displayed little affinity for binding with CTABr micelles. Linear free energy plots of LogK(B) (in CTABr) versus LogK(ow) and pK(a2) values indicated that there was a weak correlation between binding and LogK(ow) and a stronger correlation with pK(a2) for these compounds, likely reflecting the stronger binding of ionizable sulfonamide molecules in the anionic form by the cationic micelles. (c) 2016 Elsevier B.V. All rights reserved.