In this article, we study the stabilization problem for an extrusion process in the isothermal case. The model expresses the mass conservation in the extruder chamber and consists of a hyperbolic Partial Differential Equation (PDE) and a nonlinear Ordinary Differential Equation (ODE) whose dynamics describes the evolution of a moving interface. By using a Lyapunov approach, we obtain the exponential stabilization for the closed-loop system under natural feedback controls through indirect measurements. Numerical simulations are also provided with a comparison between the proposed approach and linear PI feedback controller.