Vapor-liquid equilibrium data for the ternary mixture of 1,1,1,2-tetrafluoroethane (HFC-134a) + 2,3,3,3-tetrafluoroprop-1-ene (HFO-1234yf) + isobutane (HC-600a) were measured at temperatures from 283.15 K to 323.15 K using a recirculation apparatus. The uncertainties of the experimental data are estimated within 5 mK, 0.5 kPa, and 0.003 for the temperature, pressure, and the equilibrium liquid and vapor mole fractions, respectively. The experimental data were compared with the predicted data by the Peng Robinson equation of state with the vdW mixing rule and the Wong Sandler mixing rule, respectively. The binary interaction parameters of each binary mixture were determined from the experimental data in literature. The results show that the predicted data agree well with the experimental data. It indicates that the PR equation can be used to predict VLE data of ternary mixture of HFC-134a + HFO-1234yf + HC-600a. The proposed ternary mixture has potential to be refrigerant with low GWP and excellent thermodynamic performance. (C) 2016 Elsevier B.V. All rights reserved.