화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Korean Chemical Engineering Research, Vol.54, No.3, 374-379, June, 2016
DOI10.9713/kcer.2016.54.3.374  Export Citation
이온성 액체를 이용한 바이오매스 추출에 의해 얻어진 추출물의 건조 방법
Method for Drying of Crude Extract Obtained by Biomass Extraction Using an Ionic Liquid
김슬기, 김진현†
  • 공주대학교 화학공학부, 31080 충남 천안시 서북구 천안대로 1223-24
Seul Ki Kim, and Jin-Hyun Kim†
  • Department of Chemical Engineering, Kongju National University, 1223-24, Cheonan-daero, Seobuk-gu, Cheonan, Chungnam, 31080, Korea
E-mail:
초록
이온성 액체를 보조용매로 이용할 경우 바이오매스로부터 파클리탁셀의 추출 효율은 획기적으로 개선되지만 잔류이온성 액체로 후속 농축 및 건조에 많은 어려움이 따른다. 따라서 본 연구에서는 공정 효율 향상을 위하여 이온성 액체를 이용한 바이오매스 추출물을 효과적으로 건조할 수 있는 새로운 방법을 개발하였다. 추출물을 물로 전처리하고 추가적으로 세척함으로써 잔류 이온성 액체 제거를 통해 효과적으로 건조할 수 있었다. 물 전처리을 위한 최적의 시료/물 비, 혼합시간 및 추가세척을 위한 최적의 시료/물 비는 각각 1:70 (w/v), 4분, 1:100 (w/v)이었다. 또한 진공 건조보다 마이크로웨이브를 이용한 건조의 경우 건조시간을 9배 정도 단축 가능하여 공정 효율이 획기적으로 개선될 것으로 판단된다.
When using an ionic liquid as co-solvent, the extraction efficiency of anticancer agent paclitaxel from biomass was dramatically improved. However, the residual ionic liquid had a significant negative effect on convenient and feasibility of following concentration and drying steps. In this study, a novel method was developed for the effective drying of the crude extract obtained from biomass extraction with ionic liquid. The residual ionic liquid was easily and conveniently removed by drying alone after pre-treatment and additional washing of a sample with water. The optimal crude extract/water ratio and mixing time for pre-treatment and crude extract/water ratio for additional washing were 1:70 (w/v), 4 min, and 1:100 (w/v), respectively. In the microwave-assisted drying process, the drying time was 9-fold shorter than in the vacuum oven drying process.
Keywords:Paclitaxel;Extraction;Residual ionic liquid;Removal;Drying
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