The present work deals with effective combination of ultrasonication (US) and biodegradable oxidizing task specific ionic liquid (bio-TSIL) choline peroxydisulfate monohydrate (ChPS center dot H2O) for the selective oxidation of alcohols to aldehydes/ketones. The reactions were also conducted by using a thermal heating method (TH), and the comparative studies are provided to understand the effectiveness of the ultrasound process; it was observed that the use of ultrasound significantly reduces the reaction time from 30 to 5 min. Also, a substantial energy saving (>86%) was observed when the US method (0.125 kJ/g) was compared with the TH method (0.958 kJ/g). Bio-TSIL ChPS in water as an oxidant is found to be advantageous, as it is synthesized from biodegradable and nontoxic raw materials. Incorporation of an ultrasonic energy source along with the use of biodegradable raw materials for bio-TSIL makes the process not only green but also energy efficient.