The present article reports an approach for the modification of hydrophobic polydimethylsiloxane (PDMS) with low molecular weight hydrophilic polyvinylpyrrolidone (PVP) via solution blending method to develop new PDMS-based materials with improved mechanical performance and wettability which can be used in many biomedical applications. The influence of dimethyldichlorosilane treated fumed silica (FS) on physico-mechanical properties of PDMS-PVP blends were investigated and analyzed. There was the significant improvement in mechanical, dynamic mechanical and thermal properties of PDMS-PVP blends, whereas, transparency and contact angle were slightly decreased after incorporation of FS into PDMS-PVP blends. Scanning electron microscopy revealed that the fourfold reduction in the average domain size of the dispersed PVP in the PDMS matrix in the presence of compatibilizer (PDMS-PEO block copolymer) when compared with the uncompatibilized PDMS-PVP blend morphology. By incorporation of FS into the neat PDMS matrix, the onset of degradation (T-i), the maximum rate of degradation (T-max) and overall thermal stabilities increased significantly. On the other hand, by the addition of FS into to PDMS-PVP blends, the T-i and T-max remains unaffected, but overall thermal stabilities increased significantly. PDMS-PVP blends exhibited low contact angle (similar to 45 degrees) which confirmed the formation of the hydrophilic surface. (C) 2016 Society of Plastics Engineers