Adhesive heparin coating for marine antifouling applications

Suyeob Kim; Sangwon Ko; Sung Min Kang

Macromolecular Research, Vol.24, No.7, 645-649, July, 2016

DOI10.1007/s13233-016-4091-8 Export Citation

Adhesive heparin coating for marine antifouling applications

Suyeob Kim, Sangwon Ko¹, and Sung Min Kang^†

Department of Marine Biomaterials & Aquaculture, Pukyong National University, Busan, 48513, Korea
¹Transportation Environmental Research Team, Korea Railroad Research Institute, Uiwang, Gyeonggi, 16105, Korea

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The control of marine biofouling has gained significant attention because the uncontrolled adhesion of marine organisms onto synthetic surfaces leads to serious problems. Here, we demonstrate a facile method to inhibit the adhesion of marine organisms using the sulfated polysaccharide, heparin. Heparin was conjugated with an adhesive molecule, catechol, and the resulting adhesive heparin was used as a surface coating for stainless steel, a material commonly used for marine vessels. Immersion of stainless steel surfaces in a solution of adhesive heparin resulted in a stable heparin coating. The marine antifouling property of the surface was confirmed using marine diatom adhesion assays, which revealed that the adhesive heparin coating reduced diatom adhesion by ~75%, as compared with untreated surfaces.

Keywords:adhesive heparin;mussel inspiration;marine antifouling;surface coating;stainless steel

[References]

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Kenawy ER, Worley SD, Broughton R, Biomacromolecules, 8(5), 1359 (2007)
Callow JA, Callow ME, Nat. Commun., 2, 244 (2011)
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Harris JM, Introduction to Biotechnical and Biomedical Applications of Poly(ethylene glycol), Springer, New York, 1992.
Cho WK, Kang SM, Lee JK, J. Nanosci. Nanotechnol., 14, 1231 (2014)
Chen SF, Li LY, Zhao C, Zheng J, Polymer, 51(23), 5283 (2010)
Andersson J, Sanchez J, Ekdahl KN, Elgue G, Nilsson B, Larsson R, J. Biomed. Mater. Res. A, 67, 458 (2003)
Bruinsma BG, Kim Y, Berendsen TA, Ozer S, Yarmush ML, Uygun BE, J. Clin. Transl. Res., 1, 4 (2015)
Cheng C, Sun S, Zhao C, J. Mater. Chem. B, 2, 7649 (2014)
Wei H, Han L, Ren J, Jia L, ACS Appl. Mater. Interfaces, 5, 12571 (2013)
Xie B, Pan C, Ding H, Huang N, J. Wuhan Univ. Technol., 29, 832 (2014)
Yao Y, Fukazawa K, Ma WY, Ishihara K, Huang N, Appl. Surf. Sci., 258(14), 5418 (2012)
van Bilsen PH, Krenning G, Billy D, Duval JL, Huurdeman-Vincent J, van Luyn MJ, Colloids Surf. B: Biointerfaces, 67, 46 (2008)
Bae IH, Park IK, Park DS, Lee H, Jeong MH, J. Mater. Sci. -Mater. Med., 23, 1259 (2012)
You I, Kang SM, Byun Y, Lee H, Bioconjugate Chem., 22, 1264 (2011)
Lee BP, Messersmith PB, Israelachvili JN, Waite JH, Annu. Rev. Mater. Res., 41, 99 (2011)
Lee H, Dellatore SM, Miller WM, Messersmith PB, Science, 318, 426 (2007)
Lee H, Lee BP, Messersmith PB, Nature, 448, 338 (2007)
Lee H, Scherer NF, Messersmith PB, Proc. Natl. Acad. Sci. U.S.A., 103, 12999 (2006)
Waite JH, Qin X, Biochemistry, 40, 2887 (2001)
Lee H, Lee KD, Pyo KB, Park SY, Lee H, Langmuir, 26(6), 3790 (2010)
Lee H, Lee Y, Statz AR, Rho J, Park TG, Messersmith PB, Adv. Mater., 20(9), 1619 (2008)
Sun IC, Eun DK, Na JH, Lee S, Kim IJ, Youn IC, Ko CY, Kim HS, Lim D, Choi K, Chem.-Eur. J., 15, 13341 (2009)
Lee M, Kim Y, Ryu JH, Kim K, Han YM, Lee H, Acta Biomater., 32, 138 (2016)
Kim TG, Lee H, Jang Y, Park TG, Biomacromolecules, 10(6), 1532 (2009)
Chambers LD, Stokes KR, Walsh FC, Wood RJK, Surf. Coat. Technol., 201, 3642 (2006)
Hellio C, Yebra DM, Advances in Marine Antifouling Coatings and Technologies, Elsevier, Cornwall, 2009.

[Referenced By]

[1] Noimark S, Dunnill CW, Wilson M, Parkin IP, Chem. Soc. Rev, 38, 3435 (2009)

[2] Kenawy ER, Worley SD, Broughton R, Biomacromolecules, 8(5), 1359 (2007)

[3] Callow JA, Callow ME, Nat. Commun., 2, 244 (2011)

[4] Yebra DM, Kiil S, Dam-Johansen K, Prog. Org. Coat., 50, 75 (2004)

[5] Harris JM, Introduction to Biotechnical and Biomedical Applications of Poly(ethylene glycol), Springer, New York, 1992.

[6] Cho WK, Kang SM, Lee JK, J. Nanosci. Nanotechnol., 14, 1231 (2014)

[7] Chen SF, Li LY, Zhao C, Zheng J, Polymer, 51(23), 5283 (2010)

[8] Andersson J, Sanchez J, Ekdahl KN, Elgue G, Nilsson B, Larsson R, J. Biomed. Mater. Res. A, 67, 458 (2003)

[9] Bruinsma BG, Kim Y, Berendsen TA, Ozer S, Yarmush ML, Uygun BE, J. Clin. Transl. Res., 1, 4 (2015)

[10] Cheng C, Sun S, Zhao C, J. Mater. Chem. B, 2, 7649 (2014)

[11] Wei H, Han L, Ren J, Jia L, ACS Appl. Mater. Interfaces, 5, 12571 (2013)

[12] Xie B, Pan C, Ding H, Huang N, J. Wuhan Univ. Technol., 29, 832 (2014)

[13] Yao Y, Fukazawa K, Ma WY, Ishihara K, Huang N, Appl. Surf. Sci., 258(14), 5418 (2012)

[14] van Bilsen PH, Krenning G, Billy D, Duval JL, Huurdeman-Vincent J, van Luyn MJ, Colloids Surf. B: Biointerfaces, 67, 46 (2008)

[15] Bae IH, Park IK, Park DS, Lee H, Jeong MH, J. Mater. Sci. -Mater. Med., 23, 1259 (2012)

[16] You I, Kang SM, Byun Y, Lee H, Bioconjugate Chem., 22, 1264 (2011)

[17] Lee BP, Messersmith PB, Israelachvili JN, Waite JH, Annu. Rev. Mater. Res., 41, 99 (2011)

[18] Lee H, Dellatore SM, Miller WM, Messersmith PB, Science, 318, 426 (2007)

[19] Lee H, Lee BP, Messersmith PB, Nature, 448, 338 (2007)

[20] Lee H, Scherer NF, Messersmith PB, Proc. Natl. Acad. Sci. U.S.A., 103, 12999 (2006)

[21] Waite JH, Qin X, Biochemistry, 40, 2887 (2001)

[22] Lee H, Lee KD, Pyo KB, Park SY, Lee H, Langmuir, 26(6), 3790 (2010)

[23] Lee H, Lee Y, Statz AR, Rho J, Park TG, Messersmith PB, Adv. Mater., 20(9), 1619 (2008)

[24] Sun IC, Eun DK, Na JH, Lee S, Kim IJ, Youn IC, Ko CY, Kim HS, Lim D, Choi K, Chem.-Eur. J., 15, 13341 (2009)

[25] Lee M, Kim Y, Ryu JH, Kim K, Han YM, Lee H, Acta Biomater., 32, 138 (2016)

[26] Kim TG, Lee H, Jang Y, Park TG, Biomacromolecules, 10(6), 1532 (2009)

[27] Chambers LD, Stokes KR, Walsh FC, Wood RJK, Surf. Coat. Technol., 201, 3642 (2006)

[28] Hellio C, Yebra DM, Advances in Marine Antifouling Coatings and Technologies, Elsevier, Cornwall, 2009.