Water-dispersible conjugated polymer microspheres were obtained by enwrapping with graphene oxide (GO) nanosheets. Simply mixing the polymer microspheres and GO in water results in an exclusive formation of GO-wrapped microspheres. The photoluminescence (PL) spectra of the GO-wrapped single microsphere show whispering gallery modes, in which the PL lines are broadened in comparison with bare microspheres without GO. The broadening is attributed to scattering and reabsorption of the confined PL.