The nonlinear and multimodal characteristics in many manufacturing processes have posed some difficulties to regular multivariate statistical process control (MSPC) (e.g., principal component analysis (PCA)-based monitoring method) because a fundamental assumption is that the process data follow unimodal and Gaussian distribution. To explicitly address these important data distribution characteristics in some complicated processes, a novel manifold learning algorithm, joint local intrinsic and global local variance preserving projection (JLGLPP) is proposed for information extraction from process data. Based on the features extracted by JLGLPP, local/nonlocal manifold regularization-based Gaussian mixture model (LNGMM) is proposed to estimate process data distributions with nonlinear and multi modal characteristics. A probabilistic indicator for quantifying process states is further developed, which effectively combines local and global information extracted from a baseline GMM. Thus, the JLGLPP and LNGMM-based monitoring model can be used effectively for online process monitoring under complicated working conditions. The experimental results illustrate that the proposed method effectively captures meaningful information hidden in the pnicess signals and shows superior process monitoring performance compared to regular monitoring methods. (C) 2016 Elsevier Ltd. All rights reserved.