Integrated process design and control of reactive distillation processes is considered through a computer-aided framework. First, a set of simple design methods for reactive distillation column (RDC) that are similar in concept to non-reactive distillation design methods are extended to design-control of RDCs. These methods are based on the element concept where the reacting system of compounds is represented as elements. When only two elements are needed to represent the reacting system of more than two compounds, a binary element system is identified. It is shown that the same design-control principles that apply to a nonreacting binary system of compounds are also valid for a reactive binary system of elements for distillation columns. Application of this framework shows that designing the reactive distillation process at the maximum driving force results in a feasible and reliable design of the process as well as the controller structure. (C) 2016 American Institute of Chemical Engineers