The solubilization of synthetic perfumes, eugenol (EL) and d-limonene (LN), by mixed surfactants of sodium dodecyl sulfate (SDS) and hexadecyl poly(oxyethylene) ethers (C(16)POE(n), n = 20 and 40) has been studied from measurements of the maximum additive concentration (MAC) and the distribution coefficient between the micellar and bulk phases (K). The MAC of the hydrophilic perfume, EL, in the mixed systems is smaller than the MAC predicted according to an ideal mixing rule. On the other hand, the MAC of the hydrophobic perfume, LN, is larger than the predicted value. The mixing effect of the surfactants on the MAC is larger in the SDS-C(16)POE(20) system than in the SDS-C(16)POE(40) system. In addition, the mixture of the anionic and nonionic surfactants causes the K value for each perfume to be smaller than the ideal K value. The difference between the experimental and the ideal K values for EL is larger in the SDS-C(16)POE(20) system than in the SDS-C(16)POE(40) system. In contrast, the difference in K values for LN is more pronounced in SDS-C(16)POE(40) than in SDS-C(16)POE(20), The results imply that the change in K upon mixing the surfactants may be attributed to surfactant-surfactant interactions in the mixed micelle for the hydrophilic perfume and to the effect of the Laplace pressure on the micelle-bulk interface for the hydrophobic perfume.