Emissions of multiple hydrogen production pathways from fossil sources were evaluated and compared with that of fossil fuel production pathways in China by using the life cycle assessment method. The considered hydrogen pathways are gasoline reforming, diesel reforming, natural gas reforming, soybean-derived biodiesel (s-biodiesel) reforming, and waste cooking oil-derived biodiesel reforming. Moreover, emissions and energy consumption of fuel cell vehicles utilizing hydrogen from different fossil sources were presented and compared with those of the electric vehicle, the internal combustion engine vehicle, and the compression ignition engine vehicle. The results indicate both fuel cell vehicles and the electric vehicle have less greenhouse gas emissions and energy consumption compared with the traditional vehicle technologies in China. Based on an overall performance comparison of five different fuel cell vehicles and the electric vehicle in China, fuel cell vehicles operating on hydrogen produced from natural gas and waste cooking oil-derived biodiesel show the best performance, whereas the electric vehicle has the worse performance than all the fuel cell vehicles because of very high share of coal in the electricity mix of China. The emissions of electric vehicle in China will be in the same level with that of natural gas fuel cell vehicle if the share of coal decreases to around 40% and the share of renewable energy increases to around 20% in the electricity mix of China. Copyright (c) 2016 John Wiley & Sons, Ltd.