Titania supported palladium exchanged vanadium incorporated molybdophosphoric acid (PdMPAV(1)) catalysts were prepared and characterized by FT-IR, X-ray diffraction and Laser Raman spectroscopy. The characterization results confirmed the presence of vanadium and palladium into the primary and secondary structure of Keggin ion of heteropoly molybdate respectively. The PdMPAV(1) was dispersed on support with intact Keggin ion structure. These catalysts were studied for selective hydration of nitriles to amides. The PdMPAV(1)was highly active compared to the molybdophosphoric acid containing either vanadium or palladium. The catalyst with 20 % PdMPAV(1) dispersed on TiO2 showed highest activity compare to other catalysts. A variety of nitriles were tested over this catalyst and found that the catalyst was active to yield corresponding amides. Different reaction parameters were studied and optimum conditions were established. The PdMPAV(1)/TiO2 catalyst exhibited consistent activity during reuse. [GRAPHICS] .