This paper reviews issues and applications for design of sustainable carbon dioxide conversion processes, specifically through chemical conversion, and the integration of the conversion processes with other systems from a process systems engineering (PSE) viewpoint. Systematic and computer-aided methods and tools for reaction network generation, processing route generation, process design/optimization, and sustainability analysis are reviewed with respect to carbon dioxide conversion. Also, the relevant gaps and opportunities are highlighted. In addition, the integration of carbon dioxide conversion processes with other systems including coexisting infrastructure and carbon dioxide sources is described. Then, the importance of PSE based studies for such application is discussed. Finally, some perspectives on the status and future directions of carbon dioxide conversion technology and the development and use of PSE approaches are given. (C) 2016 Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.