The carried scientific research regarding evaluation the hygrothermal effects of integration the vegetation into the building envelope was influenced with the differences in necessity to use air-conditioning in the houses, which are not surrounded with vegetation in horizontal structure and which have such vegetation during the summer time. The experimental testing is based on the precise measurements of the relative humidity and temperature, which were carried close to the building plaster in the place without influence of vegetation and between the wall and vegetation. Vegetation on the house, which was used for experimental purposes, is made up of the vine species with a thickness of 40 cm in the place where measurement was carried. Although the investigation takes longer, the paper aims to one month to show the summer time. The mathematical modelling of the obtained data was realized using the numerical as well as the statistical methods The paper aims especially on modelling the differences in relative humidity and temperature of the air and between the wall and vegetation. The dependence of temperature differences was expressed as a piecewise function using the method of Least squares of multiple regression as statistical method. Also the proportional energy to that which might be saved daily instead of its use for air-conditioning in the house was determined. The measurements as well as the used methods: showed sufficient accuracy. (C) 2016 Elsevier B.V. All rights reserved.